The placenta provides an interface beween fetal and maternal blood, supplying essential nutrients to the growing fetus. Within the placenta, fetal blood is confined to a tree-like network of blood vessels that are bathed in a pool of maternal blood. The placenta's effectiveness as a transporter of oxygen, glucose, and other molecules is critically determined by its complex geometric structure; this may be compromised in disease, with adverse consequences for fetal growth and development. This project will build on recent studies of the maternal circulation [1-3], developing analogies with models flow through porous media and exploring new multiscale approximation techniques. The project offers opportunities for analysis, computation and interaction with experimentalists.
- Chernyavsky, IL, Jensen, OE et al. (2010) Placenta 31, 44
- Chernyavsky, IL, Leach, L et al. (2011) Phil Trans Roy Soc A 369, 4162
- Chernyavsky, IL, Dryden, IL et al. (2012) IMA J Appl Math 77, 697