Course Materials for MATH35032, Mathematical Biology

Lecture Notes and Articles

The first 5-6 weeks of the term will be devoted to what one might describe as mathematical biology in the classical style and the lectures will follow sections of Jim Murray's famous text, Mathematical Biology I: An Introduction. This book is available online, though only from within the University's network (e.g. in the campus clusters or in the halls), but if you want to access it from off campus, you can install software that will allow you to use all the Library's services via the University's excellent Virtual Private Network (VPN).

Notes such as the ones below will be available for the whole term. Additionally, there will be links to some articles we'll discuss.

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Opportunities for feedback

The main channel for formal, written feedback in this module is the coursework. It will be a problem set similar to the ones provided below, but devoted to a novel application that uses the ideas from the course. You'll prepare written solutions and I'll mark them over the Easter Break, providing both written comments and a mark. In addition, the weekly examples classes provide further opportunities for verbal feedback and—for students who bring written solutions to the exercises—on-the-spot marking and written feedback as well.

Problem Sets & Solutions

The problems below are intended as a guide for students considering taking the course in 2017-18. Once the term starts, there will be new problems most weeks and I will publish the solutions at the same time as the problems.
Problems       Solutions

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Coursework & Exams

Coursework   Exams

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Reading Matter

A hyperlinked version of the lists below is available from Manchester University Library's Link2Lists system.

I studied the following—more or less mathematically-minded—books while preparing this course.

  • James D. Murray, Mathematical Biology I: An Introduction 3rd edition, (Springer, 2002). ISBN 0-387-95223-3
  • James D. Murray, Mathematical Biology II: Spatial Models and Biomedical Applications 3rd edition, (Springer, 2002). ISBN 0-387-95228-4
  • Lee A. Segel, Modeling dynamic phenomena in molecular and cellular biology (Cambridge University Press, 1984). ISBN 0-521-27477-X
  • Edda Klipp, Wolfram Liebermeister, Christoph Wierling, Axel Kowald, Hans Lehrach, Ralf Herwig (2009), Systems Biology: A Textbook, Wiley-Blackwell. ISBN 978-3-527-31874-2
  • Uri Alon, An Introduction to Systems Biology: Design Principles of Biological Circuits (Chapman & Hall/CRC, 2007). ISBN 1-58488-642-0
  • Darren J. Wilkinson, Stochastic Modelling for Systems Biology (Chapman & Hall/CRC, 2006). ISBN 1-58488-540-8

I also looked at the books below for biological background.

  • Bernhard  Ø. Palsson, Systems Biology: Properties of Reconstructed Networks (Cambridge University Press, 2006). ISBN 0-521-85903-4
  • Eric  H. Davidson, The Regulatory Genome (Academic Press, 2006). ISBN 0-12-088563-8
  • Terry  A. Brown, Genomes 3 (Garland Science, 2007). ISBN 0-8153-4138-5
    The previous edition, Genomes 2, is available online from the National Center for Biotechnology Information (NCBI) Bookshelf, a service of the U.S.A's National Institutes of Health (NIH).
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts and Peter Walter, Molecular Biology of the Cell 4th edition, (Garland Science, 2002). ISBN 0-8153-4072-9

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