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We show that a growth model for cell proliferation that
incorporates a time-lag in the cell division phase is more consistent with
certain reported data than the classical exponential growth model. Although
both models provide estimates of some of the growth characteristics, such
as the population-doubling time, the time-lag growth model additionally
provides estimates of: (i) the cell-doubling time, (ii) the
fraction of the cells that are dividing, (iii) the rate of commitment
to cell division and, (iv) the initial distribution of cells in
the cell cycle.
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